We found that decursin and DA, structural isomers on the side chain, exerted comparable potency in terms of cell-cycle arrest, apoptosis induction and impact on selected molecular targets, such as inactivation of ERK1/2, in both MCF-7 cells and MDA-MB231 cells.
Despite the presence of small effects and statistical heterogeneity among studies, our investigation shows that statins potentially exert neuroprotective effects in terms of improving cognitive outcome after TBI, with atorvastatin exerting the most protective effect on acquisition memory and simvastatin exerting the most protective effect on retention memory.
"As we see with employees in the workplace," she said, "if consumers start acting together, collectively they will be able to exert pressure and – in terms of the energy market – help each other by forcing prices down rather than benefiting shareholders and faceless corporations".
The 33 patients receiving Rituximab in the ICU did not exert any benefit in terms of ICU or long term mortality.
In contrast, RS significantly affected several groups of colonic bacteria, with the two types of RS exerting functional differences in terms of their ability to modulate the gut microbiota.
Widespread undernutrition in low-income countries continues to exert enormous cost in terms of survival among infants and young children [ 1, 2].
Taken together, the approaches used in this study have identified a number of differentially expressed miRNAs that could exert novel functions in terms of regulating muscle cell proliferation and differentiation during development.
Among CSA survivors, childhood adversities exerted a moderating effect in terms of depressive symptoms.
Pre-treatment with vitamin B6 in BM exerts neuroprotective effects in terms of reduced apoptosis in the hippocampal dentate gyrus of infant rats.
Antibiotics that reach this microbiome promote the growth of resistant bacteria over the susceptible ones, and each daily dose may exert a significant impact in terms of selective pressure [144].
