This index was designed to classify comorbidities for prognostic purposes, and posteriorly has been used as a control of the influence which comorbidity may exert in different situations.
This influence can be exerted in many different ways.
The model provides the first experimental evidence for the deleterious effect exerted in vivo by different sugars upon developing embryos and larvaes of Bufo arenarum.
Selective COX-2 inhibitors have been shown to be active as tumor chemopreventive agents in preclinical models as well as in humans [ 15, 17, 18], and to enhance the cytotoxicity exerted in vitro by different chemotherapeutics, including platinating agents [ 19, 20].
The dependent measure of interest was the amount of work in units of keypress that subjects exerted in response to the different categories of stimuli (i.e., the units in keypress that the subjects traded for viewing time); work and effort exerted for experiments has become an important focus of research in effort-based decision-making over the past decade [25] [28], [136].
APEIR is exerting influence in different ways.
Generally, Daxx is localized in the nucleoplasm and in defined nuclear structures, i.e. in the SUMO-modified PML bodies, in the nucleolus and interacts with CENP-C in the centromere, possibly exerting different functions in the different compartments.
Importantly, we note that the role of the EMC and other secretory protein biogenesis network factors appears cargo-specific, since other factors that were found in the Mrh1-GFP screen exerted qualitatively different effects in our Yor1-ΔF screen [ 77].
Among miRNAs, which were positively associated with PLA2R1 expression in this study, hsa-miR-23b and −154 exerted suppressing effects in different cancers in vitro and in vivo [ 53– 53].
Erythropoietin is a hematopoietic cytokine factor with various biological effects and its receptors are expressed in the central nervous system, which helps in normal brain development and exerts neuroprotection in different models of brain injury.
