Sentence examples for exerted directly from inspiring English sources

Thus, GLP-1RA can have beneficial effects on bone and the expression of GLP-1R in bone cells may imply that these effects are exerted directly on the tissue.

Given the data presented in previous sections, however, this role appears not to be exerted directly on cohesin recruitment.

An alternative mechanism for the augmented NO production can be provided by a regulatory effect exerted directly by estrogen, as demonstrated by several authors [28], [53], [61], [62].

It remains to be determined whether the effects of such peptides are exerted directly upon GnRH neurons, or indirectly via intermediary neurons.

This activity of probiotics may be exerted directly on dendritic cells (DCs), which are professional antigen presenting cells, as probiotic-loaded DCs can modulate the TNBS-induced inflammatory reaction through the differentiation of protective T regulatory cells [25].

This effect is not exerted directly but through its downstream effector Myosin II.

It has been proposed that uterine natural killer cells (uNK) could exert, directly or not, a positive or negative control of the early steps of implantation [3], [4].

For instance, IVM modulates the activity of nematode GABA-Cl [ 26], and can exert directly activating or potentiating effects on vertebrate glycine-gated chloride channels [ 31].

Platelets are activated in conditions that disrupt tissue homoeostasis and exert, directly and indirectly, a complex control over the different stages of inflammation, contributing to pathogen clearance, wound repair and tissue regeneration (Figs. 1, 2).

Thus, it appears possible that elevated pulmonary suPAR in burn injury exerts directly chemotactic or other pro-inflammatory functions, there-by perpetuating inflammation and tissue damage.

It's this very ability to better withstand the kind of economic pressures the United States had until recently been able to exert, either directly or through international financial institutions, which has led to recent violence in Santa Cruz and elsewhere in the wealthier white and mestizo-dominated eastern sectors of the country.