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In contrast, the combination exerted a reduction in P-ERK1/2 and P-AKT that was very moderate and tumor type specific.
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Moreover, the real rTMS exerted a considerable reduction of vertex LEPs in comparison with the sham, especially at trigeminal level.
In addition, LCM exerted a notable reduction in carbon emission, energy consumption and environmental burden compared with Portland cement.
However, the combination therapy with amlodipine and atorvastatin exerted a significant reduction in albuminuria in the present study.
Only 400 mg/kg of the extract exerted a significant reduction in ulcer index when compared with the control group.
In this model, only 400 mg/kg of the extract exerted a significant reduction in ulcer index when compared with the control group.
The control compound acarbose exerted a significant reduction of the PBG level (20.76%) and AUC (31.20%) in line with its known in vivo α-amylase inhibitory action.
Additionally, IGlar combined with OADs exerted a greater reduction in mean level of HbA1c (3 RCTs; WMD = −0.36 % [−0.54, −0.18] (−3.9 mmol/mol [−5.9; −2.0])) and was associated with a higher chance of reaching target HbA1c (2 RCTs; RR = 1.49 [1.03, 2.16]).
In accordance with the large potentiation of tonic inhibition, bath application of 3 μ m etomidate hyperpolarized the resting Vm, reduced membrane IR and exerted a clear reduction in the excitability of WT VB neurons (Table 4, Fig. 7A C).
At the highest doses, the drugs still exerted a significant reduction of the TRR 60 min after 9AC injection (i.e. 40 min after drug administration), but little or no effect was observed then after.
Similar to other studies that identified reduction in cellular viability after exposure to silver, silver ENPs utilized in this study at the dose of 20 μg/mL exerted a significant reduction in viability (27%) in TK6 cells at 4 h post-exposure.
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