(There have been multiple plagues throughout history around the world, but none have been so deadly as the Black Death, which killed an estimated one in every four Europeans, and so exerted very strong selection).
The delivered psiRNA-bcl2 induced gene-silencing in a nucleus of cancer cells, while (KLA)4 peptide inhibited cancer growth via mitochondrial apoptosis, indicating that the ternary complexes exerted very strong synergistic effects on cancer growth suppression by acting on psiRNA-bcl2 and (KLA)4 peptide simultaneously.
It is worthy of note that bortezomib exerted very strong effect on senescence of fibroblasts incubated in hypoxic conditions.
This implies that ALK fusion itself exerts very strong driving forces for tumorigenesis, in other words, that ALK fusion is a driver mutation, not just a passenger mutation.
Although Case (2002) reported that income exerts very strong effect on health status, however when health care services are provided to the public free of charge or subsidized, the effect of income may be weak or irrelevant to health seeking behaviour.
This would appear to be logical, as pesticides exert a very strong selection pressure, decreasing the impact of migration, mutations and genetic drift on the evolution of resistance.
In this respect, heavy metals exert a very strong selective pressure on bacterial communities, causing structural changes in the community itself and are usually accompanied with a reduction in the microbial biomass (Kandeler et al. 2000), and with a loss of biodiversity (Deng et al. 2007; Laplante and Derome 2011).
Unquestionably as ideas they exerted a very strong influence on the development of equestrian statues in the 16th century.
This is important: a recent paper from the Federal Reserve Bank of Chicago found that even after accounting for other measures of unemployment, the number of workers counted as "part-time for economic reasons" exerts a very strong effect on wage growth.
