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NOTCH cascade involves functionally non-redundant genes that appear to exert unique and specific functions [ 6].
The nuclear receptor Ftz-F1, the ETS-domain transcription factor Ets21c and the bZIP protein Fos all exert unique and overlapping functions in promoting full malignancy of the ras V12scrib tumors, but only Ets21c is sufficient to induce malignant tumors in cooperation with activated Ras.
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These results demonstrate that symmetrically and asymmetrically modified nucleosomes exist in vivo, and might exert unique biochemical downstream effects.
Our findings regarding the involvement of different subunits in response to high-B stress indicate distinct roles for B-toxicity tolerance among paralogs and the possibility that 26SPs containing one or multiple specific RP subunits (at least among RPN2a, RPN8a, RPT2a, and RPT5a) are assembled to exert unique functions, especially in ameliorating high-B-induced DSBs in the RAM.
At present, the majority of agents used for the treatment of IBD are felt to function through the inhibition of inflammatory mechanisms, or specifically blocking inflammatory cytokines, and the addition of an antiangiogenic compound may exert unique therapeutic benefit.
Independently of their neuronal properties, NTs exert unique cardiovascular activity.
Some White House watchers are predicting that Kushner will eventually be situated at Trump's re-election campaign, but he will, nonetheless, continue to exert unique influence.
Its products can exert unique cytoprotective effects.
Alternatively HIF-1α may exert unique effects on the β cells [ 82].
Fibroblasts that surround and interact with cancer cells have been called cancer-associated fibroblasts (CAFs) which can exert unique roles to support cancer cell growth [ 1].
Like pro-IL-1α, nuclear pro-IL-33 appeared to exert unique biologic activities independent of cell surface receptor binding [ 14- 16].
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