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In human cells, expression of the β-chain is dispensable for surface expression of the FcεRI, however, the human β-chain has been shown by Kinet and colleagues to exert two important amplifier functions.
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This was achieved by using a unique combination of two targeting ligands, RGD and anginex (Anx), which bind specifically to two important angiogenic markers, αvβ3 and galectin-1, respectively, and exert angiostatic activity as well [ 7, 85].
Two important questions are whether all lncRNAs are functional and how they could exert a function.
Two important inflammatory mediators, histamine via H1 receptors and PGE2 acting largely via EP2 receptors, exert opposing effects on [Ca2+]i in human ASMCs.
The present study has helped to answer the following two important questions: (i) is VGB present at the target site; and (ii) is VGB exerting a response from the target receptor?
Two important notes.
Two important points.
Two important points follow.
Two important characteristics of most cytokines are pleiotropy, defined as the ability of one cytokine to exhibit diverse functionalities, and redundancy, defined as the ability of multiple cytokines to exert overlapping activities.
Unlike other family 18 chitinases, however, the Chi18H8 seems to exert antagonistic selective activity against four important plant pathogens, coherently with the suppressive nature of the soil from which it was isolated.
We reasoned that genes exerting two or more of these biological functions play an important role in the establishment and functioning of metabolic networks [22].
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CEO of Professional Science Editing for Scientists @ prosciediting.com