Sentence examples for exert repressive from inspiring English sources

Thus it appears that vg is not sufficient to exert repressive effects on lms that could have fully explained the largely complementary expression of the two genes in the wing discs.

However, SREBPs (1 and 2) can exert repressive effects on ABCA1 expression, decreasing cholesterol efflux [ 29, 30].

Based on the high complementarity of the recognition sites on their targets, the plant miRNAs exert repressive roles mostly through target RNA cleavages at post-transcriptional level [ 2].

A third pathway involving CikA exerts repressive effects on circadian gene expression, possibly by promoting dephosphorylation and suppressing RpaA activity [ 89, 92].

The observed EMT and neuroectodermal commitment over other lineages pointed to the possibility that BRD4 may be exerting repressive functions on differentiation genes of this lineage.

To determine whether translational repression is involved when miRNAs exert their repressive effects against nonsense mRNAs, we constructed a modified luciferase reporter that has a fragment containing two in-frame miR-125b miREs followed by an additional in-frame stop codon fused to the 3′ end of the luciferase ORF (TAA-2E).

A single miRNA is thought to able to exert its repressive effects on hundreds to thousands of transcripts, meaning that specific miRNAs may have very wide-ranging effects on cellular phenotype6,11.

Recently, PGF2α was proposed to exert a repressive effect on testosterone release by testis Leydig cells [37], [38].

Indeed, rather than being activated, RTN1* may be stabilized by another binding protein that would prevent miR-195 from binding to RTN1* to exert a repressive effect.

These results suggest that Ivermectin requires active PP2A/PP1 to exert its repressive effect on the WNT-TCF pathway.

Ago2 and Dcr2 exert a repressive effect on expression of euchromatic genes by modulating transcriptional elongation (Cernilogar et al. 2011).