"exert its role" is correct and usable in written English.
You can use it when referring to an entity or entity's action that is having a specific effect. For example: "The government must exert its role in providing healthcare to its citizens."
It is possible that ETK may exert its role in bladder cancer through regulating these pathways.
NapA is directly activated by oxidation through ROS, allowing it to enter the nucleus and exert its role as a positive transcription factor.
In fact, it was observed in both animal models of bleomycin-induced fibrosis and in lung tissues of IPF patients that HIF 1- α is overexpressed and may exert its role in early stages of fibrogenesis as it was localized in areas of active fibrosis and in normal areas of IPF lung but not within the fibroblastic foci which represent areas of established fibrosis [ 42].
We conclude that transgenic IgNrg1β1 strictly requires Bace1 processing to exert its role in muscle spindle formation.
However, in some sexually reproducing organisms, such as Drosophila melanogaster and Caenorhabditis elegans, DMC1 is missing and other RAD51 homologs exert its role [ 55, 56].
These data suggest that BMI1 may exert its role in human MB pathogenesis at least in part through modulation of the expression of cell adhesion genes, potentially via BMP pathway repression.
Hence it is involved in the binding specificity of Ir-LBP and plays a key role in ligand binding as confirmed by mutational analysis (which also showed that it exerts its role in cooperation with Arg 53).
When SPARC is secreted from stroma cells, it exerts its role on neoplastic progression in a paracrine fashion (Porte et al, 1995; Le Bail et al, 1999).
Alternatively, it is possible that maspin exerts its role only in the nucleus at the level of gene or chromatin regulation and thus indirectly affects the cell-matrix interaction or differentiation state and is released only as a consequence of cell damage or necrosis [20 27].
Mutation of p21WAF1/CIP1 is rare in different types of human malignancy, therefore, it is suggested that p21WAF1/CIP1 exerts its role in tumorigenesis mainly on expression level.
Cr is a key factor in determining the passive current of the alloy; whereas, in the transpassive region, Mo exerts its role by inhibiting the local dissolution of metals via attachment to the outermost surface of the chromium oxide film.
