Sentence examples for exert its functional from inspiring English sources
This variant maps to an intergenic region but it was hypothesized that it may exert its functional effect via the TNFAIP3 gene.
Likewise, it is possible that Mek/Erk may be under the control of other effectors, including PI3K, to exert its functional role.
DNA methylation can exert its functional influence through a range of different processes, including direct effects on transcription factor binding, or indirectly via changes to post-translational histone packaging and modulation of chromatin conformation and function [43].
There is preliminary evidence that SNAI2, implicated in malignant tumor dissemination via initiation of EMT, may partially exert its functional effect via upregulation of PAI-1 expression, and this has been demonstrated in canine epithelial cells.
We next examined how β1 blockade exerted its functional effects on HCC1954 cell growth and survival by surveying β1 signaling intermediates.
The accepted role of miRNAs is the steering (inhibition) of the abundance of gene products, which is mechanistically exerting its functional infraction mainly in the cytoplasm.
Although the mechanisms underlying these phenomena remain obscure, the finding that Smad7 entirely localizes in the nucleus in the course of the cell cycle suggests that Smad7 may exert its inhibitory effect through a functional complex with nuclear factors responsible for cell cycle progression.
The TNC struggled to establish a functional government and exert its authority in the months that followed the fall of the Qaddafi regime.
Hence, it is of considerable relevance to define a drug's requirement for functional p53 to exert its antitumoural activity.
In case ceftriaxon exerts its action via functional EAAT2 expression regulation, co-application of dihydrokainate will impede its clinical effect.
It is not known how electrical stimulation of central or peripheral target structures exerts its effects, although a neuronal functional block seems the most likely option.
