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It is not known why indomethacin is effective, but it must exert its effect differently than other non-steroidal anti-inflammatory drugs.
Thus, PACAP cannot exert its effect although it can cross the BBB or enter the endothelial cells.
Since miRNA is non-translational, it must exert its effect through regulating target genes.
Given YKS's stress-modifying capabilities, we hypothesized that it could exert its effect by impacting the HPA axis, and more specifically, by regulating GR expression in the hypothalamus.
It was thought to exert its effect through decreasing the viability of T helper type 1 cells and attenuating the interaction of T cells with macrophages.
It may suggest that ceftiofur hydrochloride exert its effect mainly on the IgM isotype.
It is also plausible that NO can exert its effect alone, without acting through other signalling molecules.
In addition, bacteria may acquire efflux pumps that extrude the antibacterial agent from the cell before it can reach its target site and exert its effect.
Therefore, it is unlikely that in mice, class2 can exert its effect by reacting with TG2.
These data indicate that 5-azacytidine does not exert its effect on NMD by inducing translational readthrough and that it therefore inhibits NMD by a novel mechanism.
Since MinC does not affect the GTPase activity of FtsZ it is thought that MinC requires dynamic FtsZ polymers to exert its effect [30].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com