However, the effect of autophagy on IL-1β production was demonstrated only in murine cells, and no information was available whether similar effects may be exerted in human cells.
Thus, according to these findings obtained from in vivo and in vitro studies, the inhalation of graphene nanomaterials would be expected to exert toxicity in humans, as in experimental animals.
Probiotic bacteria, mainly belonging to the lactic acid bacteria (LAB) family, are well known to exert beneficial effects in human or animal health.
CRF1 and CRF2 receptors are differentially expressed and exert distinct function in human and murine hair follicle pigmentary units [6], [8], [30], [31].
Lipid emulsions thus exert differential effects in human volunteers and mice in vivo.
If the indole may exert similar effect in human gastric mucosa, it might contribute to the accessibility of H. pylori to gastric mucosa cells.
Other members of this family, such as SFRP2, SFRP4 and SFRP5 [ 4, 5], were also found to exert their roles in human cancers.
These data suggest that BMI1 may exert its role in human MB pathogenesis at least in part through modulation of the expression of cell adhesion genes, potentially via BMP pathway repression.
The aim of the present study was to evaluate whether AG, UAG, Ob and the GLP-1R agonist exendin-4 (Ex-4) exert cytoprotective effects in human islet endothelium.
Our data support the potentially high antiarrhythmic potency of late INa inhibition as this approach reduces SR-Ca2+-leak in murine and human atrial CMs by interfering with the activity of CaMKII and PKA, both of which are known to exert deleterious effects in human cardiac disease.
