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Moreover, all these information would indirectly implicate that other organs would exert important role in the inflammatory status observed in FIRS.
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Biofilms exert important roles in environmental- and public health processes occurring within intertidal systems.
As previously introduced, Shh and Numb exert important roles in the regulation of adult neurogenesis [ 22, 24, 26– 33, 34] 34].
Many studies have revealed that lncRNAs exert important roles in biological processes, including roles in cell differentiation, transcription, imprinting, chromatin modification, and others [ 36, 37].
Increasing evidence indicates that lncRNAs exert important roles in a wide range of biological processes, including cell differentiation, chromatin remodeling, immune responses and tumorigenesis [ 6– 8].
In the present study, the expression of MyD88, NF- κB p65 (nuclei) and p-I κB α were induced by oxLDL in VSMCs from WT mice, which was impaired markedly in VSMCs from TLR4−/− mice, suggesting that MyD88/NF- κB signaling exerts important role downstream of TLR4 in inflammation during VSMC foam cell formation.
However, in many atherogenic conditions, inflammatory reaction often appears in VSMCs and exerts important roles.
We identify characteristically different patterns of seismic activity distribution in different tectonic blocks, with bi-, or even tri-peak distribution of seismic concentration in South Tibet, which may suggest that crustal architecture and composition exert important control role in lithosphere deformation.
The present results implied that accumulated dolichyl-P in the brain may exert an important role in the depression of the P-gp at the BBB, which may suggest valuable clues to promote function of the pump at the BBB in AD.
The mitochondria exert an important role in apoptosis, i.e., the mitochondrial membrane becomes more permeable leading to the release of potentially toxic proteins.
Some insist that R&D and innovation exert an important role in long-run growth (Romer [1990]; Aghion and Howitt [1992]).
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