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Several lines of evidence indicate that also in biological systems, decasaccharides are sufficiently long to exert full effect on LPL.
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It takes about two years for changes in monetary policy to exert their full effect on inflation.
Our results further suggest that exogenous S1P is not sufficient by itself to exert a full effect on EC migration as evidenced by data showing that inhibiting SphK1 with either CII or down-regulation of SphK1 with siRNA attenuated S1P-induced migration.
Therefore, both binding sites are functional and required for miR-200c to exert its full effect on the MSN 3' UTR.
Thus, it is not surprising that many histone PTMs exert their full effect only in conjunction with other marks.
Rather, the drug has to be used in combination with conventional chemotherapeutics to exert a full effect in xenograft models and perhaps also in human cancer.
At a concentration of 0.3 μM, NAGly was slow to exert its full effect on NCXpm currents, the degree of inhibition increased with time and a steady-state value was reached over 200 250 s after initial application.
As for MSN, mutated constructs show that miR-200c binding to these sites specifically is required for down-regulation and both binding sites are functional and required for miR-200c to exert its full effect on the FN1 3' UTR.
Retinal movement toward TM5 exerts its full effect upon transition to Meta IIb, reflected in a weakening of the hydrogen bond to Glu122.
This means that cumulative measures of the impact of the epidemic, which include infections prior to when the full effect is exerted, provide a less substantial indication of the effectiveness of this intervention [50].
Preacher Clinton in full effect.
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CEO of Professional Science Editing for Scientists @ prosciediting.com