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Roulstone, V. et al. BRAF- and MEK-targeted small molecule inhibitors exert enhanced antimelanoma effects in combination with oncolytic reovirus through ER stress.
If so, protected NK cells could not exert enhanced cytotoxicity despite prevention of TiA.
More importantly, LPS-treated Tregs exert enhanced function in vitro and remain suppressive in vivo [ 86].
Radiation therapy combined with these targeted therapies may exert enhanced antitumor activity through synergic action.
SSc patients have high numbers of aberrant circulating monocytic EPCs that exert enhanced angiogenesis but are impaired in vasculogenesis.
A recent study suggests that TRAIL can exert enhanced cytotoxic activity in cells arrested in G1 or G2 phase.
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Over recent years tremendous progress has been made towards understanding the molecular and cellular mechanism by which estrogens exert enhancing effects on cognition, and how they act as a neuroprotective or neurotrophic agent in disease.
Interestingly, this strain exerted enhanced hemolysis in vitro compared to the pandemic isolates (Supplementary Fig. 5a) and therefore phenocopied the hapA-minus mutants of the pandemic isolates with respect to its toxicity towards A. castellanii (Supplementary Fig. 5c).
It is therefore concluded that DCs engineered by Ag85A gene exerts enhanced anti-tumor immunity against bladder cancer and this study might provide a meaningful mode of action with the use of Ag85A engineered DC vaccination in anti-cancer immunotherapy.
Biological characterization revealed that several compounds exerted enhanced anti-proliferative activity against human umbilical vein endothelial cells (HUVECs) and several cancer cell lines and high specific protein kinase and angiogenesis inhibitory activities.
Interestingly, GC exerts enhanced antitumor activity than that of tRV (P < 0.05).
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