Bortezomib, a proteasome inhibitor, may exert efficacy in TNBC through its multiple cellular effects.
Thus, there is a continuing need for agents that exert efficacy equal to or greater than that achieved with TCAs and that have a more favorable side-effect profile (Class Ia, recommendation A [see Supplementary material]).
Since the inversion from R to S is lower in humans than in mice, it remains to be answered to what extent R-flurbiprofen may exert efficacy in multiple sclerosis.
Haloperidol, a typical antipsychotic, is non-selective and binds to a broad range of receptors, exerting efficacy mainly through the antagonism of dopamine receptors.
Aerosolized therapy offers a way to administer high doses of antibiotics that exert their efficacy against pathogens directly at the site of infection while reducing systemic toxicity.
CR extracts do not contain estrogenic compounds: they exert their efficacy through mechanisms linked to the presence of dopaminergic, noradrenergic, serotoninergic and GABAergic acting substances, but no estrogenic activity can be expected.
Although most psychologists would without hesitation accept the causal interaction of minds and bodies, a small but growing number of empirical researchers have insisted that the evidence supports some version of epiphenomenalism, the thesis that mental states, while caused by physical happenings, exert no efficacy in return.
Together, these results demonstrate that our highly potent HIV-1 specific shRNA sequences exert comparable efficacy as to the published sequences.
It is notable that the median survival in the group which received additional injection of hMSC-scFvEGFRvIII was extended over the group of animals without an additional injection, suggesting that hMSC expressing scFvEGFRvIII exert therapeutic efficacy on established intracranial tumors in vivo.
Platelet microbiocidal proteins and konocidins have shown to exert strong efficacy against bacteria and fungi [ 19].
D-Cycloserine may not always exert optimal efficacy, as there is evidence that, for example in social anxiety patients, the achieved fear inhibition may not be sustained [ 14].
