Sentence examples for exert critical from inspiring English sources
Recent evidence suggests that dynamic three-dimensional genomic interactions in the nucleus exert critical roles in regulated gene expression.
From the impact of digital social media on political action and the rise of predictive technologies in speculative real estate to new ways of mapping temporal conditions of a site and the evolving role of information in how designers see, understand, and act on space, ICTs exert critical influence.
However, significantly more IgG-reactive components are secreted, and these include those associated with Als3 and Hyr1, two GPI-anchored cell wall proteins that exert critical roles in cell wall assembly, growth and fungal virulence [50] [53].
Particularly, while the central domain is poorly conserved, the C-terminal domain contains two regions that are highly conserved from yeast to mammals, suggesting that such regions might be preserved during evolution to exert critical centromere functions (Figure 1) [23].
Our data also suggest that the anti-virulence properties of the IgG2b mAb may be linked to its capacity to recognize β-glucan epitope(s) on some cell wall components that exert critical functions in fungal cell wall structure and adherence to host cells.
The p65 and p50 subunits of NF-κB have been demonstrated to exert critical activity in the transcription of MMP-2/MMP-9 genes.
The IRE1α-mediated generation of spliced XBP1, a potent transcription factor, exerts critical effects on differentiation, lipid metabolism, pro-inflammatory cytokine production, and the HIF-1α-dependent hypoxia pathway in various cell types12,29,30,31.
Kahn broke with Oscar Stonorov in 1947, but Ms. Tyng continued as a member of Kahn's staff until 1964, exerting critical influence on his work, including designs for the Yale Art Gallery and the Trenton Bath House.
This Bug Factor (often excluded from tropical eco-lodge brochures), in fact, maintains healthy rain-forest, clean drinking water, effective pollinators, and exerts critical climate stabilization, among many other things.
Therefore, it appears that HIF-2α exerts critical functions in normal and transformed hematopoietic cells regardless of its expression levels.
Since it is well known that ApoE exerts critical antiatherosclerotic and anti-inflammatory actions, we decided to evaluate whether ApoE downregulation mediates the detrimental effects of CC2238/ αANP.
