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In addition, host proteins are often subjected to post-translational modifications, which exert an additional layer of regulation.
However, although often neglected, extracellular nucleotides exert an additional more subtle function as negative modulators of immunity, or as immunedepressants.
Small amounts of fish oil supplementation does not exert an additional effect on the concentration of CLA C18 2 cis-9, trans-11 as compered to exclusive use of soybean oil.
Feeding small amounts of fish oil blend plus soybean oil does not exert an additional effect on the concentration of CLA C18 2 cis-9, trans-11 in relation to the exclusive use of soybean oil.
This supports the opposing view, that genes in the HLA class I region indeed exert an additional influence on the risk of MS, and confirms that the class I allele HLA-A*02 is negatively associated with the risk of MS (OR = 0.63, P = 7×10−12) not explained by linkage disequilibrium with class II.
However, they also exert an additional indirect inhibitory effect via modulation of nucleotide-dependent channel gating.
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That her brother and her mother, now 90, also lived uptown exerted an additional pull.
More importantly, it further shows that smelling the flavour of a food while observing its grasping exerts an additional and significant CS facilitation.
However, we cannot completely exclude that one of the remaining effector proteins or another bacterial factor that is translocated via the T1 system exerts an additional stimulation.
Preliminary results indicate that MYCN binds the p21 promoter, suggesting that in MYCN-amplified neuroblastoma MYCN exerts an additional suppressing activity on p21 expression at transcriptional level (data not shown).
Furthermore, we observed a strong impairment in irradiation- and intoxication-induced nuclear translocation and foci formation of Nbs1 in the HO15.19 cells (Figures 6 and 7), suggesting that Myc exerts an additional level of control, apart from gene regulation, in the DNA damage-induced activation of the MRN complex.
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