It has been suggested that members of the HOX gene cluster exert an important molecular switch mediated via downstream factors such as BMP4, Activin A, or VEGF.
Because increased nuclear S1P leads to upregulation of expression of fatty acid metabolism genes and increased mitochondrial activity, it might exert its beneficial function on muscular dystrophy by promoting a switch to a slow twitch muscle metabolism.
The general agreement between reconciliation tests of alternative topologies (not shown) indicates switching events exert a considerable influence, but does not alter the approximate numbers co-divergence events.
Thus, in contrast to LAX3, AUX1 might exert a pivotal role in rhizogenesis/xylogenesis switching, in accordance with its role in other developmental processes, including in vitro organogenesis (Kakani et al., 2009; Péret et al., 2012).
Therefore, we are proposing that Nfix exerts its functions through a double mechanism, involving both a switch to an oxidative phenotype and a delay of the regenerative process.
The force-generating elements exert forces on FliG, while FliM and FliN, with FliG, comprise a switch complex that controls the direction of rotation.
It has been reported that supposed partial agonist agents may exert a ligand-dependent modulation of micro-switches relevant to receptor activation and to submaximal coupling to intracellular effectors [ 47].
Considering the crucial role of Beclin 1 in modulation of the interaction between apoptosis and autophagy, we speculate that spermidine may exert a neuroprotective action by regulating the autophagy/apoptosis switch node Beclin 1.
"Flick a switch, any switch".
