Exact(1)
One reason why shielding of NK cells against TiA may not be followed by enhanced cytotoxicity could be that any NK cell, once activated by an appropriate target, is not able to exert a second cytotoxic hit against a second target.
Similar(59)
Although fuel specific reactions do not exert a first order effect on flame propagation, the products of the initial fuel decomposition affect the concentrations of C1C4 intermediates, whose subsequent reactions are responsible for the observed differences in the overall flame reactivity among all isomers.
And all the while the tidal friction will be exerting a second effect; it will be pushing the moon farther away, just as it has already pushed it out more than two hundred thousand miles.
The geometry of structures developed within the step-over zone exerts a second order control on the location of deposits within the Castle Hill camp and fluids were focussed into areas of enhanced permeability during deformation.
The distribution of 137Cs within the three profiles suggests that a remnant outwash terrace exerts a first-order control over the deposition of overbank alluvium.
Submarine channels are often conduits for these flows, exerting a first order control on turbidity current flow processes and resulting deposit geometries.
The positive correlation between zircon εHf(t) values with the Cu reserves, as well as zircon δ18O values with the Cu/(Cu + Pb + Zn) ratios of the deposits indicate that the magmatic sources exerted a first-order control on the volume and metal assemblage of deposits in the QHMB.
It has been hypothesized that sorafenib could exert a dual activity: the first one directly on neoplastic cells and the second one trough a modulation of pro-thrombotic cytokines [ 16].
And with the All Blacks forwards in the supremacy and Australia's key men Quade Cooper and David Pocock unable to exert a decisive influence, two second-half penalties sent a capacity Kiwi crowd away into the Auckland night in delight.
They also suggested that this QTL could exert a pleiotropic gene action, first affecting plant height, then ears per plant, and finally grain yield.
On the other hand, in non-expressing cells, chemotherapeutics have been shown first to induce P-gp expression and, second, to exert a selection of resistant cells during the course of chemotherapy [ 18- 21].
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