Sentence examples for exert a novel from inspiring English sources

We previously found that α-eleostearic acids (ESA), a conjugated tri-enoic fatty acid, obtained by in vitro screening from Pleurocybella porrigens mushrooms, exert a novel type of programmed cell death, which is AIF-dependent.

In therapies for pancreatic ductal adenocarcinoma model, PF-562,271 inhibits migration of cancer cells, cancer-associated fibroblasts (CAFs), and tumor-associated macrophages (TAMs) [ 100], indicating that PF-562,271 may exert a novel mechanism in inhibiting cancer metastasis by altering the tumor microenvironment.

These data demonstrate that PYCARD exerts a novel inflammasome-independent role during chronic Mtb infection by containing the bacteria in granulomas.

Given the observation that an additional Rai1 homologue exists in Drosophila which contains the Rai1 catalytic domain, we hypothesized that Cuff might be a germline-specific Rai1 variant, which exerts a novel function in germline cells (Chen et al, 2007).

Thirty years on, the Discworld has grown so solid and so weighty that any new novel has to exert a great deal of narrative power just to get that world moving at a decent pace.

To examine if any of the 40 novel repressors could exert a similar effect as INSIG1, candidate repressors were tested for their ability to down-regulate elevated luciferase ratios resulting from SCAP overexpression.

Novel therapeutics which exert a positive effect on these targets, may reinforce energy delivery from the mitochondria [ 109].

As described above, although ET-1 is a potent pro-fibrotic peptide and bosentan exerts a novel anti-fibrotic effect, the detailed molecular mechanism explaining these observations has still remained unknown.

Here we report the novel mechanisms how ALK5 inhibitors exert a therapeutic effect on a mouse B16 melanoma model.

A novel theory the 'biotic pump' suggests that evaporation and condensation can exert a major influence over atmospheric dynamics.

But those traits exert a heavy price".