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Absorption of water in the liquid methanol is verified to exert a large effect on extinction and is included in the analysis by treating the two limiting cases of time-dependent liquid-phase diffusion and perfect liquid-phase mixing, along with the quasisteady gas phase.
As each miRNA can influence the level of numerous protein targets, even slightly dysregulated miRNAs can exert a large effect on cellular behavior.
If the daily dose of antipsychotic drugs is 501 to 1000 mg/day, antipsychotic drugs exert a large effect on ANS activity and decrease ANS activity.
We did not observe any between-group differences in estimated cell type proportions, suggesting that variation in cell type distribution would be unlikely to exert a large effect on the differences observed in our sample.
Flow through a tracheostomy/ endotracheal tube (ETT) is mainly laminar and governed by the Hagen-Poiseuille equation: Flow = pressure × radius 4 × π / length × viscosity × 8 The radius of a tube has the predominant influence on gas flow; small changes in tracheostomy/ETT ID can exert a large effect on flow.
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This is because the genotype usually has no effect on language ability, but occasionally exerts a large effect, when occurring in the context of a set of other risk genotypes.
The estimates of environment-specific QTL effects revealed that each site and season exerted a large effect on the expression of both yield and photosynthate remobilization or accumulation traits but less so on expression of photosynthate carbon assimilation traits.
Unlike the Dalmatian, where the heritability of deafness has been estimated to be as high as 0.75 for a trichotomous trait [ 3], the highest heritability estimate in the JRT in this study of 0.31 for a trichotomous trait is not indicative by itself of a single major locus exerting a large effect.
Since the INSIG2 rs7566605 C-allele has been proposed to exert a larger effect in individuals already predisposed to obesity, we investigated the effect of the variant in the obese subgroup of the combined study sample (n = 3,878), with a mean BMI of 32.8 kg/m2, however, no genotype effect was found (data not shown).
There are two subsites within the UP element: promoter proximal and distal; either can function independently, although the proximal subsite may exert a larger effect on promoter activity.
Another possible explanation for this small effect on caspase-8 expression could be that the dose of 10 mg GS-9450 was too low to exert a larger effect on peripheral T-cell apoptosis while maximal concentrations were reached intra-hepatically.
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