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Two important questions are whether all lncRNAs are functional and how they could exert a function.
It is possible that they exert a function respective to other PADI genes, cell types, or stimuli than the ones we queried.
This may suggest that the CDK1-dependent stimulation of resection could exert a function by overcoming the inhibitory effect of Rad9 bound to H3-K79me.
Furthermore, as mitochondrial and ER membranes are continuously and concertedly remodeled, it is not surprising that membrane-shaping proteins can also exert a function in regulating the ER-mitochondria coupling.
This raises the question of whether they could exert a function in transcript processing, i.e. help process the putative primary transcripts generated from the divergent promoters into shorter RNAs.
This suggests that alternative splicing could be a molecular mechanism whereby membrane bound type B hexokinases, perhaps also in other plants, may become soluble and thus exert a function inside the nucleus.
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Thus, it is unlikely that RibH2 is exerting a function different than LS.
The posterior layer of the thoracolumbar fascia exerts a function in load transfer between the spine and the legs [ 37- 40].
In spite of all these reports of peroxisomal LDH association, it has never been universally accepted that LDH indeed enters the peroxisome and indeed exerts a function in peroxisomes, because a targeting signal or targeting mechanism could not be identified.
First, Rod1 exerts a function at the plasma membrane, as it is essential for the endocytosis of the glycerol/proton symporter Stl1, and required for the efficient internalization of Jen1 upon glucose treatment.
It is believed that Na+-channel function is affected by phosphorylation [ 23] and PKC exerts an function in the phosphorylation of Na+ channels.
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