The effect was specific to ABCA1; indeed in a similar experimental set up, ABCA7 [27], [27], the closest ABCA1 relative in the A class of ABC transporters, exerted little influence on the phagocytic behaviour of recipient cells.
In tumors, there is only one report showing that DP T cells infiltrating a cutaneous T cell lymphoma exert a tumor-specific MHC class-I restricted lysis [15].
Glucocorticoids, a class of steroid hormones, exert dramatic effects on metabolism and immune response during periods of stress and lead to catabolism of lipids, carbohydrates, and proteins while increasing glucose availability in the bloodstream [ 83, 84].
Sweden is undertaking a two-year study of the social effects of a 30-hour workweek -- proving that Thorstein Veblen and his theories about the leisure class still exert a bigger pull on the European imagination than Adam Smith does.
SIRT1, a class III histone deacetylase, exerts inhibitory effects against LKB1 by targeting it for degradation, subsequently promoting anoikis resistance and EMT.
Polyamines are a class of biogenic amines that exert multiple in vivo effects on cellular processes in most organisms [ 16].
Micro RNAs (miRs), a class of non-coding small RNAs exert a pivotal role in several biological processes ranging from development and differentiation to apoptosis and proliferation.
Carotenoids are a class of terpenes of commercial interest that exert important biological functions.
Thus, it is likely that MHC class I alleles exert a similar neuroprotective effect in HIV-infected individuals irrespective of treatment status.
Our findings confirm the cellular biological basis that Class I HDACs exert a tumor-promoter effect in HCC through the induction of cell proliferation, invasion and metastasis.
