As an exemplar, the LCA trials began in 2007, but are only now, in 2013, beginning to enroll patients in phase III studies (clinicaltrials.gov NCT00999609).
On every trial, either exemplar of each category had an equal chance of being drawn as the memory item, with the constraint that the memory item could not be repeated on consecutive trials.
On category-match trials, another exemplar of the memorized item appeared as a distractor.
On category-match trials, another exemplar from the category of the memory stimulus appeared as a distractor in the search display.
Participants viewed a continuous stream of faces in which each trial-unique exemplar was repeated 1 4 times consecutively (Fig. 1 A), while performing an incidental gender-judgment task on a subset of target faces indicated by a colored frame (these target trials were modeled separately and excluded from our analyses).
On 25%% of the trials, the memory item appeared as the memory probe; on another 25%% of the trials, the other exemplar (of the memory item's category) appeared; and on 50%% of the trials, a completely different object appeared.
Using a multicenter, North American weaning trial as an exemplar, we describe our early experiences as clinical researchers with patient and family engagement.
The model is now being evaluated through parallel randomised controlled trials in two exemplar chronic conditions.
For one, attention may have been guided to the second exemplar in the category-match trials because it was visually similar (although not identical) to the memory item.
Thus, the results of Experiment 2 do not support the idea that the attentional guidance that we found in Experiment 1 was due to the semantic relationship between the information in WM and the exemplar in the category-match trials.
