Your English writing platform
Discover LudwigSuggestions(2)
Exact(5)
These appear to be confined to metazoans, and may form a secondary executive pathway that evolved after the symbiosis that led to the formation of the eukaryotic cell type.
Specifically, the executive pathway involves a dysregulation of thought and action that is primarily characterized by a core deficit in inhibitory control [ 11].
Sonuga-Barke [ 11] argues that these two pathways likely give rise to an ADHD diagnosis of the Combined subtype, and that the executive pathway is more likely associated with more severe and generalized cognitive impairment.
It has been hypothesized that the executive pathway receives inputs from the dorsolateral prefrontal cortex to the dorsal portion of the neostriatum, as well as reciprocal connections from subcortical regions, including the dorso-medial sections of the thalamus.
While the deficient executive pathway is assumed to involve an insufficient regulation of thought and action primarily characterized by a core deficit in inhibitory control, the dysfunctional motivational pathway is hypothesized to link behavioral symptoms, task engagement, and a biologically embedded alteration in reinforcement mechanisms.
Similar(54)
These findings provide support for the separable motivational and executive pathways in current models of ADHD [ 11, 12].
The sustained attention task used in the current study required the unique activation of alerting, orienting and executive control pathways, which is a variation from more commonly used tests of sustained attention such as the rapid visual information processing task.
Amphetamine exerts its behavioral effects by altering the use of monoamines as neuronal signals in the brain, primarily in catecholamine neurons in the reward and executive function pathways of the brain, collectively known as the mesocorticolimbic projection.
These findings suggest that even in the absence of alcohol or substance use, youth with familial alcoholism already exhibit similar deficits in functional connections in important executive functioning pathways as those seen in alcoholics (Schulte et al. 2012).
Recent models suggest that the core symptoms of attention-deficit/hyperactivity disorder (ADHD), namely inattention, hyperactivity and impulsivity, could result from dysfunction of two neurodevelopmental pathways: the executive and motivational pathways [ 1].
One important change reflected in this dual-pathway conceptualization is that the executive and motivational pathways are not regarded as competing theories, rather that deficits in both processes are thought to give rise to the manifestation of ADHD [ 12].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com