CF designed and executed the literature searches.
SAT executed the literature review, contributed to the critical analysis, and composed the manuscript.
Additionally, we identified 67 associations between GCs and target genes where the regulator executing the regulatory effect was missing in the literature.
The effectiveness of the present formulation and solutions are firstly validated by executing the comparison studies with results available in the literature.
JK lead author, contributed to all elements of the study; specifically: study design; primary literature reviewer; responsible for executing the search for abstracts and grading for level of evidence; data abstraction, analysis and presentation; primary manuscript writer and responsible for all encompassing and all subsequent revisions throughout the editing process.
JK lead author, contributed to all elements of the study; specifically: study design; primary literature reviewer; responsible for executing the search for abstracts; data abstraction, analysis and presentation; primary manuscript writer and responsible for all encompassing and all subsequent revisions throughout the editing process.
Significantly more critical appraisal topics of discussion identified in the revised paper were found in topic (1): 'Preparation for executing literature search', and 'Strategy of literature search', every CAT task element of topic (2), and in topic (3): 'Relevant clinical conclusion regarding clinical problem'.
The sole author of this paper has conducted the literature review, designed the methodology, executed the study, carried out the data analysis, and prepared the manuscript.
To mitigate reliability threats, we executed the non-deterministic algorithms 30 times, as recommended in the literature.
Will Johnson Security execute the idea?
