Next, the matched genes were submitted to execute pathways and GO enrichment.
Necroptosis is an important form of lytic cell death triggered by injury and infection, but whether mixed lineage kinase domain-like (MLKL) is sufficient to execute this pathway is unknown.
They are responsible for executing apoptotic pathways, or programmed cell death, and for activation of cytokines such as IL-1β and IL-18.
Nevertheless, there are some contradicting opinions that question the involvement of caspases and modulation of Bax/Bcl-2 in the gamma-tocotrienol executed apoptotic pathways [ 6, 7, 14, 15].
Mature neutrophils contain few mitochondria, although the amount of these apoptosis 'orchestrating' organelles is sufficient to trigger and execute common pathways of apoptosis and to express the signals essential for the effective clearance of them [ 89, 91].
Macrophages may well exert differential distress/trophic signalling cascades, executing death pathways in some cell types (Burguillos et al., 2011) while aiding in debris removal and repair in others (Kondo et al., 2011).
In Arabidopsis, the miR390-TAS3-AUXIN miR390-TAS3-AUXIN miR390-TAS3-AUXINtes impoRESPONSEnctions in leaFACTORlopment ARF lateral root formation [ 21].
Our data indicate an intrinsic apoptotic pathway executing anoikis as evidenced by preferential caspase-9 activity and cleavage.
Intrinsic apoptosis is the principal autonomous self-destruct pathway executed by cell somas.
Finally the synthetic N-IMPLY logic networked to the Rac pathway executed the N-IMPLY pattern of ruffle formation.
These caspases then execute the apoptotic pathway to trigger DNA fragmentation and membrane blebbing, two hallmarks of apoptosis.
