Although there are tissue-specific signatures of miRNA repression or miRNA mRNA mutual-exclusiveness for several highly expressed miRNAs, the pattern of miRNA target gene expression is complicated, especially in the central nervous system (CNS) [2], [15] [16].
It is the battle of inclusiveness versus exclusiveness and for the acknowledgement that the region's states are multi-ethnic, multi-religious and multi-tribal entities.
Further studies are needed to elucidate the mechanisms for the mutual exclusiveness of EZH2 and HDAC4 and to determine therapeutic targets for the distinct epigenetic-specific cancer phenotypes.
This finding is in line with previous results from our lab that additionally showed the exclusiveness of increased MEP amplitudes for mental rotation compared with several control conditions [ 17].
In a recent interview, albeit conducted just before he was propelled into his new job, Mr Clarke was inclined to put the blame for the apparent social exclusiveness of the top universities more on the deficiencies of state secondary schools than on the universities' admissions policies.
In 1997, for example, the editors of Nature condemned the "withering exclusiveness" of their own articles and trumpeted a renewed concern for readability.
If in Becker's day firms feared that customers would punish them for inclusiveness, today firms fear customers will instead punish them for exclusiveness.
To relate the decrease in information about the current stimulus to the increase in the exclusiveness of the current stimulus encoding, we have, for each time point after the stimulus transition, extracted the encoded image and compared that to the amount of information that the neurons convey about the previous and the current image.
In the current study, all 25 KRAS positive samples were wild-type for EGFR, supporting the general mutual exclusiveness of the two mutations.
Interestingly, the selection is based on markers that do not have any functional relevance for being a CSC, and the exclusiveness of the CSC population in the ability to initiate cancer as well as its uniqueness in CD133 positivity has been questioned recently [ 74].
