In the pharmaceutical space, Veeva Systems (an Emergence portfolio company) built a customer relationship management (CRM) solution focused exclusively on solving customer acquisition problems in pharma.
Granted, I see the world through a very particular lens as the co-founder and CEO of Chomp, a technology company focused exclusively on solving the app discovery problem.
We need to bring in a new class of players on the playing field of technology who will create new technology exclusively for solving social problems and adapt the existing technology for the same purpose, without any thought of making personal profit out of this.
It may also be that the sensitivity of the assays was too low for the purpose and that detection of products failed due to the amount of material used in the reaction; this, however, is a general problem that can be solved exclusively by a simple and permanent cell culture model (low budget) or by an exhausting experimental setup of large scale primary cell cultures (very high budget required).
At this time, no efficient query can be done on RCSB Protein Data Bank (17) to select easily and exclusively protein structures containing solved PTMs.
Methods relying exclusively on information from solved 3D structures have been developed, analyzing features such as the geometric arrangements of residues (Fetrow and Skolnick, 1998), surface geometry (Peters et al., 1996), electrostatics (Bate and Warwicker, 2004), energetics (Elcock, 2001; Laurie and Jackson, 2005) and chemical properties (Ondrechen et al., 2001; Tong et al., 2008).
The past seven years revealed the conservative illusion of protecting America exclusively by a mammoth military has two logical flaws: In the modern world no problem can be solved by an exclusively military response.
If you solve exclusively with numbers, you are increasing your chances of buggering something up if you plug and chug it in a calculator.
Considering that Social Security's shortfall remains 18 years away and can easily be solved through revenue increases alone, many progressives argue that focusing exclusively on the program's funding gap is a wrongheaded premise.
