Traditional approaches in animal husbandry, and also the approaches to solve these problems, are often and primarily based on unidirectional technical solutions, in which control is exclusively exerted over both dead matter and living entities.
Because ecdysteroids act also on non-ABCB1 expressing (sensitive) cell lines, our results demonstrate that they do not or not exclusively exert their adjuvant anticancer activity as ABCB1 inhibitors, but other mechanisms must be involved, and they opened the way towards their in vivo bioactivity testing against various cancer xenografts.
At least for SINV virus, our results demonstrate that resistance to PKR is exerted exclusively at translational level and that probably only involves overcoming eIF2 phosphorylation.
Estrogen actions were thought to be exerted exclusively via nuclear estrogen receptors ER α (from ESR1 gene) and ER β (from ESR2 gene).
In practice, we are exploiting the gCSCs as an immunosuppressive cell population to evaluate the role of hypoxia given the gCSCs propensity to recapitulate many of the hallmark features of malignant gliomas, including immunosuppression; however it is unlikely that hypoxia exerts effects exclusively to this population.
Accordingly, CA exerts not exclusively beneficial effects, but can lead to impaired performance in a task-dependent way.
Conversely, α value approaching zero indicates that the particular reaction mechanism exerts its influence exclusively through interactions with other AT1RGRN parameters.
If so, because germ plasm is maternally inherited, it would be expected to exert its influence exclusively in the early stages of development.
The high mortality rate (approximately 50%) occurred among paralarvae exposed to the highest Cd exposure (1000 μg/L) and the related environmental significance prompts us to analyze transcriptional and biochemical effects exerted by Cd exclusively at 10 and 100 μg/L CdCl2.
This suggests that RS2 exerts its effect by exclusively increasing the rate of ADP release.
