Sentence examples for exclusively activates from inspiring English sources

Here, we report that FGF23 exclusively activates FGFR4 on cardiac myocytes to stimulate phospholipase Cγ/calcineurin/nuclear factor of activated T cell signaling.

This discrepancy can be resolved by predicting the existence of additional layer(s) of control, a likely possibility being a transcription factor under direct control of pfsir2 which exclusively activates upsC var genes.

We included FGF18 treatments in the experiments, in parallel for comparison, as FGF18 exclusively activates FGFR3, in human adult articular chondrocytes.

Data are expressed as mean of 3 quantified biological replicates ± SEM. (C ) Gene-expression analyses revealing comparable induction of Nfkb2 mRNA upon LPS treatment in WT MEFs, those mostly activate RelA p50 dimer and Relb −/− Nfkb1 −/− MEFs, which exclusively activates RelA p52 dimer.

For instance, it has been observed using a combination of glutamate binding-deficient and G protein coupling-deficient receptors that the mGlu1 receptor triggers Gq-coupled signalling through cis- and trans-activation, while Gi/o and Gs are exclusively activated through cis-activation (Tateyama and Kubo 2011).

However, FGF18 exclusively activated FGFR3 without detectable activation of FGFR1.

To evaluate the relevance of the CB1 receptor in the physiological control of striatal BDNF expression, we selectively manipulated MSN activity by the designer receptor exclusively activated by designer drug (DREADD) pharmacogenetic technique.

Kotz is also applying the pharmacogenetic DREADD (designer receptor exclusively activated by designer drugs) approach to define orexin action for physical activity energy expenditure.

While the constructs used in the experiment are widely accepted as generally implicating left versus right activity, neither the RFFT nor the COWAT can be said to exclusively activate a given hemisphere.

An extreme case of target selectivity is found for the peroxisome proliferator-activated receptor gamma (PPARγ), an intracellular target of LPA that is exclusively activated by unsaturated acyl species of LPA (Tsukahara et al., 2006).

Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are novel tools for the dissection of circuitry mediating behavior and neural function.