Sentence examples for exclusive pattern of from inspiring English sources

Mehmet Altan from the University of Texas MD Anderson Cancer Center in Houston, USA, and colleagues demonstrated this mutually exclusive pattern of B7-H4 and PD-L1 activity two independent populations a finding that could explain why drugs designed to boost anti-cancer immunity by blocking PD-1/PD-L1 signaling only work for a fraction of patients with breast cancer.

A similar relationship was found between K-Ras mutations and presence of oncogenic C-RAF, consistent with the mutually exclusive pattern of RAF and RAS mutations in human tumors [36] [37] (Figure 3B).

While coincident mutations in these genes have previously been reported in cancers of the large intestine [17], PIK3CA and KRAS mutations have typically exhibited a mutually exclusive pattern of occurrence in endometrial cancer [18], [19].

Another interesting observation of our study is the absence of a mutually exclusive pattern of DNA methylation changes within FEM modules.

Third, do putative epigenetic driver events targeting specific gene modules or signalling pathways exhibit a mutually exclusive pattern of deregulation within individual tumours, similar to what is observed at the copy number level [ 10]?

These studies revealed a mutually exclusive pattern of FOXL2 and SOX9 protein expression at the cellular level, reflecting the antagonistic relationship of these molecules and their respective pathways during sex determination.

However, their artifact representations are not yet specified enough to support exclusive patterns of tool use.

Expression data indicate mutually exclusive patterns of AmphiGoosecoid and AmphiVent1 genes in early amphioxus embryo, which makes the above-mentioned mechanism plausible in amphioxus as well [2].

We have shown that these mutually exclusive patterns of expression are controlled by a self-organizing system of feedback loops that involve WG and DPP, but whether the feedback is direct or indirect is not known.

The two transcription factors exhibit mutually exclusive patterns of nuclear localization in β-cell; constitutive nuclear expression of a mutant Foxo1 is associated with the lack of Pdx-1 expression [26], [27].

This is consistent with mutually exclusive patterns of positive staining for GLUT1 and Nuc-pYStat5 at the global tumor level.