First, our definition of affected genes was arbitrary which might lead to the inclusion of unrelated background genes or exclusion of truly affected genes, and both situations would lower the clustering power of DAVID.
False discovery correction was not applied in the selection of the set of differential expressed genes because such approaches, while reducing type I errors for null associations can also increases the type II errors for those associations that are not null resulting in the exclusion of truly chemical responsive genes from the gene list [ 59, 60].
If it "alternately reflected and justified bourgeois culture, denying by exclusion any inconvenient, unpleasant or truly subversive facets of life," it was equally capable of contradicting itself with complexity and brilliance.
We predicted that the use of more-stringent diagnostic criteria would result in the exclusion of many patients who truly had RA, because of an absence of detailed medical notes, rather than any doubt about the diagnosis.
This is consistent with the idea that the Kinesin-13A subfamily is ancestral to the Kinesin-13B group, since such a relationship would mean that the Kinesin-13A subfamily is not truly monophyletic (to the exclusion of Kinesin-13B).
This is critical because these are the kinds of enterprises that will most likely engender the breakthroughs necessary to truly address social and economic exclusion.
Such a strategy could have led to potential exclusion of many patients who were not truly anuric, but we only excluded five patients because of low urine output in that hour.
Consecutive and prospectively performed MRI and histopathology interpretations were compared without re-assessments or patient exclusions to ensure that the reported data truly reflected routine clinical practice.
"They have truly lived in a sort of exclusion".
In each case, the percentage of SP cells was markedly diminished by treatment with verapamil, which is an inhibitor of the pumps responsible for the exclusion of Hoechst dye, indicating that this population truly represented SP cells.
