Nonsegregation of STR-haplotypes within the family allowed exclusion of all intervals except the interval located on chromosome 6 which could not be further refined.
This type of missing data is called "nonignorable missing," and the simple exclusion of such "interval-measured" data can bias results (Little and Rubin 1987; Schafer 1997).
Furthermore, different from mRNA arrays, where the abundance level for most of the probes is above the detection limit (DL) of the instrument; in miRNA arrays, we often have a large portion of miRNAs that are expressed below DL [ 13], resulting in the type of missing data called "non-ignorable missing", and the simple exclusion of such "interval-censored" data can significantly bias results [ 14].
Data in Table 3 and Figure 4 were analyzed using Bayesian inference of 0.975 confidence intervals for the difference of means; exclusion of 0% from that interval was taken as a significant deviation between samples.
Associations with head circumference were similar for subjects who had used the air samplers at least 5 days, for subjects who had not forgotten it in a room from which they were absent (or forgotten it for < 12 hr), and after exclusion of observations with an interval between the end of use of the sampler and storage in a refrigerator of > 90 days during part of the June September period.
We address the problems of determining consistency and of finding a solution for sets of three-point relations expressing exclusion of a point from an interval, and for sets of four-point relations expressing interval disjointness.
With exclusion interval of 2 years, the relative risk of benign brain tumour was significantly higher in the exposed cohort than in the controls.
As control a resampling of the SD categories was performed (10000×; BEDTools "shuffleBed") with the following conditions for the random intervals: locate to the same chromosome and with the same interval sizes as the input SD data set, non-overlapping intervals and exclusion of annotation gaps.
Exclusion of women with longer interbirth intervals might have induced a degree selection bias, for example, if PM2.5 sources contributed to subfertility, and subsequently longer interbirth intervals and fertility treatment associated preterm birth.
Since uncensored MEMS data might overestimate non-adherence 28 adherence data were censored according to information derived from notes and interviews (eg, exclusion of self-reported non-monitoring intervals or extra openings, and intake of doses taken from another source than MEMS).
