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No changes in cell size following Plxdc2 misexpression were observed, excluding this potential mechanism as the possible cause of neural tube thickening.
Exploratory analysis excluding this potential outlier improved the test retest correlation for this domain (Paper First, r = 0.81, 95% confidence interval = 0.59 0.91 and combined, r = 0.72, 95% confidence interval = 0.56 0.83).
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However, future studies with interstimulus intervals allowing for a full return of the hemodynamic response to baseline levels are required to unequivocally exclude this potential confound.
However, their small numbers warrant more research to exclude this potential influence.
To exclude this potential confounding effect we mapped C.Prot down to yeast where large-scale unbiased data are available.
In any case, the lack of ObRb upregulation in our studies excludes this potential mechanism and suggests that most probably amylin may activate signaling pathways downstream of Jak2.
However, according to our analysis of drug change at an individual patient level, we believe we can exclude this potential explanation as being the crucial one.
To exclude this potential confound, no additional spatial smoothing was applied in our study, but due to scanner-related properties, fMRI data are likely to display a certain level of inherent spatial smoothing.
We required that each alignment segment have at least three exact bp matches directly adjoining the consensus donor and acceptor splice site in order to exclude this potential artifact.
22 It is possible, however, that those with missing data were the most seriously ill, and it was more difficult to obtain and record accurate data for the MINAP database (eg, those who died prior to hospital arrival or in the ED), and we cannot exclude this potential source of bias.
However, existence of initial defects such as weld defects cannot be entirely excluded and this potential cracks are to be evaluated to determine if initiated cracks do not lead to component failure instantly.
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