Exact(16)
Cortical rim is absent excluding severe hydrocephalus and confirming hydranencephaly.
A cutoff value of >28 mg/dl provided a sensitivity of 84.6% but a rather low specificity of 60.0% in excluding severe hyperkalemia >6.0 mmol/l (AUC = 0.75).
However, none of these signs had very good negative likelihood ratios, meaning that they were not useful for excluding severe dehydration in children.
A cutoff value of X ≥ −37.035 resulted in a sensitivity of 92.3% and a specificity of 72.0% in excluding severe hyperkalemia (accuracy = 78.9%).
No cutoff value of minimum glomerular filtration rate excluding severe hyperkalemia could be derived from serum blood samples (r = −0.055, p = 0.74).
The clinical scoring system had adequate negative predictive value for excluding severe immunosuppression.
Similar(44)
The authors did exclude severe injuries from their population, but were unable to adjust for injury severity within their sample.
Conclusion: In patients with unstable angina in class IIIB according to Braunwald classification, the negative cardiac troponin test did not exclude severe coronary artery disease, which in the majority of patients required revascularization without any additional non-invasive testing for ischemia.
Normal S100 values excluded severe cerebral damage.
We did exclude severe GERD and big hiatal hernias, but many of these patients have some GERD symptoms; indeed, 48% of our patients did have intermittent reflux symptoms, so we did not exclude them, we excluded only severe GERD.
Indeed, the randomized, controlled trauma study was designed specifically to exclude severe TBI in order to avoid adding heterogeneity to the already heterogeneous trauma population.
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