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Based only on the novel internal exons (excluding novel terminal exons), these data contribute an additional 2.7 Mb of novel transcribed sequence to the annotated transcriptome.
Moreover, the set of microRNAs subjected to mRNA predictions was limited to 12 microRNA candidates validated by RT-qPCR (excludinovelvel miR-d5 and SNORD15).
The reason for the performance difference between combinations including and excluding "novel" predictions is that AUGUSTUS often reports a transcript with an incorrect first or last exon (i.e. it reports an additional exon, data not shown).
After excluding novel TE insertions within other existing TEs in the reference genome or the annotated piRNA clusters, we found that 7.3 27.5% (median: 19.6%), 4.2 31.6% (median: 21.6%), 1.2 6.2% (median: 5.6%) of novel TE insertions from the Cridland, Linheiro, and TEMP annotations, respectively, showed evidence of the de novo signature in each sample (Materials and Methods).
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By excluding novels, chapbooks, tracts, ballads, and fairy tales, it effectively decided what counted as children's literature and what did not.
. 78)" Similarly, in State v. Gomes 79) the state supreme court shied away from the general acceptance standard and instead relied upon Rule 403's probative/prejudicial test to exclude novel expert testimony as to the unreliability of eyewitness accounts.
. 33)" Similarly, in State v. Gomes 34) the state supreme court shied away from the general acceptance standard and instead relied upon Rule 403's probative/prejudicial test to exclude novel expert testimony as to the unreliability of eyewitness accounts.
There's an important debate waiting to be had about how our current peer review and esteem systems exclude novel approaches to cure.
The filtering also excluded novel alleles absent from either control dataset; such putative new mutations are considered further below.
They won't care that there are at least six excluded novels that are weighing heavily on my conscience - if only there had been space for them.
The current paper focuses on the influence of host genotypes and diversity on clonal competition and we believe that excluding these novel isolates did not affect our interpretations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com