Daily routine 8 h-creatinine clearance (8-CLCR) was measured to all admitted patients (23 pm to 07 am), excluding measurements where serum creatinine ≥1.2 mg/dL.
Excluding measurement-related effects, two obvious possible explanations remain for the sizable deviations from perfect linear correlation.
We addressed this issue first by performing technical replicates of all measurements, and excluding measurements with standard deviations ≥1.0.
For comparison, we subsequently performed a subanalysis, excluding measurements with large intrasubject variation according to the manufacturer's guidelines (30, 31).
Sensitivity analysis was performed by excluding measurements taken within 6 months of diagnosis, those patients with suspected renal failure, and patients under 18 years of age.
For the analysis of central blood pressure and augmentation index, excluding measurements with an operator index <75 (178 measurements of 1,046; 27 patients, 6 from routine care and 21 from intensive treatment) did not change the results substantially.
Valid data on patellar and tibial bone Pb concentrations (excluding measurements with uncertainties greater than 15 or 10 ppb of Pb for patella and tibia respectively) were available in a subsample of 153 and 95 women respectively.
While some studies [ 6] have shown comparable predictive power even when excluding measurements within 200 m of highways, these studies were in more urbanized and highly-trafficked settings than Warwick, and the airport itself is relatively small.
When prediction equations excluding measurements of lactate were derived from 50% of the data and then applied to the remaining holdout sample, the AUC for hospital and ICU mortality was 0.820 ± 0.01 and 0.873 ± 0.01 respectively.
Thus, both SCI (specular component included) and SCE (specular component excluded) measurement conditions are included in most color measuring instruments today.
