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After excluding induced births (by medication or by caesarian sections), and preeclampsia, SGA and stillbirths, the associations between maternal height and length of pregnancy became weaker in our study.
When we used Cox regression to include induced abortions in the analysis, the hazard ratio for spontaneous abortion was almost the same (adjusted hazard ratio 1.11, 95% confidence interval 1.02 to 1.21) as the risk ratio in the main analysis (binomial regression) excluding induced abortion.
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We identify a structural sensitivity which excludes "induced heterogeneity" explanations for the origin of this state.
We excluded induced abortions from the main analyses.
We excluded induced abortions from the binomial models and restricted analyses to participants with information on all variables (n=802 680).
It is equally possible that had they excluded induced labor, for which preterm SGA is a common indication, that the association with prematurity would no longer have been evident.
To assess the role of induction, we restricted the main analyses to spontaneous onset of delivery (excluding medically induced deliveries plus all elective caesarian sections plus acute caesarian sections before onset of labour).
Furthermore, a normalization of the data to a common altitude of 400 km has been applied to possibly exclude variations induced by the orbit decay.
To investigate the role of TLR-2 and TLR-5 in greater detail and to exclude signalling induced by the cagPAI-dependent injection of bacterial effectors, we next tested several cell lines for their susceptibility for injection and phosphorylation of CagA.
To exclude differences induced by food intake, all HFD-fed mice were pair-fed.
In summary, we can exclude artifacts induced by the His-tags.
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