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We conducted sensitivity analyses using alternative approaches to assess the potential impact of excluding enrolled cases with unknown KRAS-mutation status.
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Most reports excluded enrolled neonates or were retrospective or uncontrolled in design.
The midwifery and nursing professional category includes midwives, registered nurses and nurse managers; it excludes enrolled nurses.
No patients were excluded once enrolled and measurements were completed.
We excluded beneficiaries enrolled in risk contract Medicare Advantage plans because their administrative databases are incomplete.
We considered whether children with nonsevere pneumonia or URTI characterized by coryza, cough, sneezing, and sore throat should be excluded or enrolled and analyzed as separate control groups.
20 We excluded patients enrolled in Medicare for renal disease or disability as they might differ from those eligible for Medicare on the basis of age.
We excluded patients enrolled in capitated health plans during any part of the study year (n = 170,232) because they may have received screening tests while in these plans for which claims were not submitted.
Among these cases, we excluded those enrolled in healthcare maintenance organisations or those lacking part B Medicare insurance (coverage for outpatient care), as we could not ascertain comorbidities and use of chemotherapy for these patients (Klabunde et al, 2006).
This study's lack of randomization should be considered as another limiting factor because the study design did not permit us to exclude patients enrolled after the introduction of the VAC-system.
Second, as pointed out by Rodu [ 34], the authors excluded workers enrolled in their cohort from 1971 to 1975 because of "ambiguities" in questionnaire coding, despite an earlier report on snus and cardiovascular disease from this cohort [ 35] being based only on workers enrolled in the years excluded by Luo et al (1971 to 1974).
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