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After sequentially excluding, as per the exclusion criteria, 120 281 patients with prior diagnosis of cardiovascular disease, 2253 with invalid dates, 439 740 aged <35 years or ≥75 years, 114 123 with missing Townsend scores, 28 148 patients with a pre-existing diabetes diagnosis, and 9824 patients with prior statin use, the analysed cohort consisted of 1 072 800 patients (see table 1).
Similar(59)
Data from these patients were included by extrapolation when using the two original populations, but not for the post hoc analysis with a more recent Danish population (in which patients with a birthweight <3 kg were excluded as per the comparison population; n = 304).
19 papers were excluded as per our criteria, leaving 531 included studies.
Of these 95 were excluded as per pre-specified exclusion criteria (Fig. 1) and inability to sample patients for 2 months (September and October) due to logistic reasons.
The arm including Fluoxetine treatment was excluded as per inclusion criteria.
Lactose intolerance was excluded as per subject profession or previous diagnosis.
Carcinomas located exclusively within the esophagus were excluded, as per the most recent WHO criteria [ 21].
A total of 312 women were excluded as per the exclusion criteria afore-described.
Twenty-six abstracts were immediately excluded as per the inclusion criteria (these included one Chinese paper, three duplicates, and two editorials).
Italian sera originated from a previous study, where patients with acute infections or immunosuppression were excluded as per study protocol [ 25].
Online supplementary file 1 contains a list of full text articles that were retrieved, reviewed and excluded as per the inclusion criteria.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com