By randomly excluding an increasing amount of GEO data sets and array samples from the training data, we investigated the minimum number of samples necessary to robustly build the probe effect model in TileProbe.
However, enterococci exhibit virulence through mechanisms such as adhesion and biofilm formation, translocation through eukaryotic cell layers, or release of proinflammatory molecules, and the absence of an observable effect in the models used does not exclude an increased pathogenicity of the transconjugants.
Our results are consistent with previous findings but the study is too small to exclude an increased risk.
The upper CI value does not exclude an increased risk for CWD-endemic county residents, but it is inconsistent with a dramatic increase in that risk.
Given the observational study design, our study does not exclude an increased risk of PPH by the use of therapeutic LMWH if similar obstetric measures are taken.
However, we cannot exclude an increased participation of circulating hemangioblasts (hematopoietic/endothelial precursor cells) in early tumor vascularization in D849N-mutant mice.
Our review highlights the paucity of available data and does not exclude an increased risk for isoniazid-resistant TB after IPT.
Analyses were limited by small numbers and incomplete testing of isolates, but findings do not exclude an increased risk for isoniazid-resistant TB after IPT.
Likewise, phase IV studies in patients with type 2 diabetes have neither confirmed nor excluded an increased hazard ratio for rosiglitazone (12, 13), and, similarly, large randomized multicenter trials in high-risk diabetic patients with substantial use of rosiglitazone neither confirm nor exclude increased risk (14, 15).
The present study also had a greater proportion of men, a higher prevalence of current smokers and a high mean BMI, as well as other unknown factors that could potentially affect calcitonin levels; however, in the absence of clinical correlations, we cannot completely exclude an increased prevalence of C-cell pathology in the present population.
