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We restricted our analysis to women with cycle lengths ranging from 20 35 days (n = 337), excluding a subject with a 14-day cycle length.
The main reasons for excluding a subject involve circumstances that make it unsafe for the subject to undergo an MRI, a PET scan, or a lumbar puncture, such as metal or shrapnel in the body, unstable medical conditions, or current use of certain medications.
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Initial treatments and touch-up treatments were reasons to exclude a subject from the study.
Therapeutic use of rest or a partial response to rest should not exclude a subject's illness from classification as CFS.
The 1994 case definition stated that any past or current diagnosis of major depressive disorder with psychotic or melancholic features, anorexia nervosa, or bulimia permanently excluded a subject from the classification of CFS.
Since one of the subjects in the right hand training group did not participate in the post-test, in the post-test analysis only, we excluded a subject trained on corresponding sequences on the left hand to ensure that sequences employed were matched across groups.
Any of the following excluded a subject from participation in the trial: evidence of any eye disease except refractive error, history of ocular trauma or intraocular surgery within the last 6 months, ocular inflammation or infection within the last 3 months, astigmatism more than +2.0 dioptres and ametropia of more than ±5.0 dioptres.
If a report was not accurate enough to include or exclude a study subject, we retrieved paraffin embedded tumour samples (PET) and original sections.
Consistent with previous studies [Gong et al., 2011; Modinos et al., 2012], a "leave-one-out" cross-validation method was used which involved excluding a single subject from each group and training the classifier using the remaining subjects; the subject pair excluded were then used to test the ability of the classifier to reliably distinguish between categories (i.e. patients vs controls).
We also excluded a second subject who died of septic shock 24 days after device implantation, leaving 11 subjects for analysis.
Since some subjects may not have been seen every year, incidence rates were calculated after excluding any subject with a physician billing or hospital discharge records with a diagnosis of the target diagnoses between 1991 and 1995.
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