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A wide diversity of cell subsets are labelled in the Cx3cr1 gfp/+ system, including NK cells, which can be excluded only with a specific γc-deficient background (Auffray et al., 2007).
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The trials also included patients with varying risk of malignancy; some studies mandated a history of cancer for inclusion, some excluded those with any cancer, while others excluded only those with a history of non-skin cancer.
GP's excluded only patients with very severe psychiatric disorders (mania or psychosis), patients with terminal illness or an inadequate command of the Dutch language.
The following inclusion/exclusion criteria were followed: haplotypes with more than 3 dropouts for F2R and IL6 genotypes were excluded, only individuals with complete haplotype information for both genes were included and only haplotype pairs with a frequency ≥1% have been included in the analysis.
They did not use the current definition of overactive bladder and excluded only subjects with urinary tract infection.
Copenhagen cases and controls excluded Only cases with at least 2 years between blood sample and glioma/glioblastoma diagnosis included.
We analysed results according to a modified intention to treat principle, whereby we excluded only patients with no follow-up measurements at all.
The study of Lidegaard et al, 8 however, excluded only those with selected cancers and coagulation disturbances, while a number of studies 15 18 did not exclude any such morbidity-related idiopathic cases.
N=205 participants (3.8%; n=14 events) had at least one missing data; we considered data imputation (R transcan function 26) and excluded only those with missing values in more than four covariates of interest (n=6 men and n=3 women).
The divergent results, compared to our study, could perhaps be explained by different exclusion criteria at baseline where Hedlund et al. seem to have excluded only those with present wheeze.
We excluded only 26 cases with incomplete responses on the scale items and, as far as we could determine, these appeared to be responses missing at random.
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