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Two-thirds are older adults and, as you suggested, the research that supports evidence-based treatment, how we care for people, has largely excluded older adults from the trials.
Indeed our study design excluded older individuals with severe hypertension and/or coronary heart disease and our data reveal that both total fat mass and central adiposity were significantly associated with cognitive decline independently of the presence of hypertension and intimal media thickness.
Previous population-based studies have excluded older age groups.
We observed that a minority of trials dealing with severe infections excluded older patients.
We also excluded older women from our analyses because of possible secular differences in use of ultrasounds for fibroid diagnoses.
The lack of association may in part be related to our exclusion of hospitalized/unstable patients, which we suspect excluded older patients.
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(The new title excluded Old Contemporaries, but let that lie).
We purposely excluded old, established brands.
We ruled out non-working celebs who essentially live off royalties (Barbra Streisand, for example), and we also excluded "old Hollywood" types like Elizabeth Taylor.
We excluded old people who had suggestive cognitive deficit according to the Mini-Mental Status Examination (MMSE), and severe hearing deficit (observed by self-report and/or the own researcher).
A sensitivity analysis that excluded the four studies using internal comparators and a sensitivity analysis that excluded old or poor quality studies did not significantly change the direction or the magnitude of the effect of the meta-analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com