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Most of the studies that were excluded focused on assessment of myometrial or cervical invasion rather than evaluation of the lymph nodes.
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We excluded interventions focused on testing and surveillance unless they specifically facilitated prevention, and educational or media campaigns focused on increasing individuals' level of knowledge about a particular health problem.
We have excluded studies focused on assessing spatial access to trauma centres because our aim is to summarise methods used for epidemiological investigation rather than those associated with healthcare resource planning.
Furthermore, studies were excluded that focused on standardized techniques, e.g. nursing languages or Minimum Data Set.
Upon further analysis of the remaining 26 trials, 11 were excluded: 2 focused on patients over 70 years of age, 4 (OPTIMAL, NEJ002, EURATAC, and WJTOG3405) on patients with EGFR mutations, and 5 on the combination of chemotherapy and TKIs.
Excluding studies focused on INH prophylaxis in infants (Madhi et al).
Of these, 25 were excluded based upon the aforementioned criteria, 3 were excluded because they focused on neuroimaging, and 1 was excluded because it included children.
We therefore excluded studies focusing on mentoring employees in corporate settings.
Women < 30 years of age at the start of the study were excluded to focus on mid-life and older women.
We excluded trials focusing on high-risk groups or prevention of psychosis because of the possible ethical implications of targeting interventions at these individuals.
In our review, we excluded studies focusing on aquatic environments (e.g. marine protected areas, MPA) or studies solely related to hydrological problems.
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