They can, however, affect macromolecular thermodynamic stability through preferential exclusion from the protein surface, which raises the protein free energy in proportion to the preferentially excluding exposed surface area [18].
This suggests that the smaller caliper would produce a smaller mean difference between matched pairs without losing too much power by excluding exposed subjects with no appropriate match.
Brumos et al. [ 21] compared the partial leaf transcriptomes of Citrus rootstocks Cleopatra mandarin (a good shoot Cl− excluder) and Carrizo citrange (a poor shoot Cl− excluder) exposed to NaCl and KCl stress using a cDNA microarray covering 6,875 putative unigenes.
The relationship between blood cadmium and tubular proteinuria was strong, even when we excluded occupationally exposed participants.
Our study included pesticide drift from outdoor applications only and excluded workers exposed within the application area.
In sensitivity analyses, we excluded women exposed to antipsychotics, antidepressants, and insulin and insulin analogues (ATC codes: N05A, N06A and A10A).
We also excluded patients exposed to acid suppressive drugs before the day of surgery to isolate the effect of these drugs as administered in the immediate postoperative period.
As a delay could occur between onset of psychosis and ascertainment by the registry, we also excluded those exposed to loss between ages 13-20 years. 13-20 years
We excluded one exposed subject with hyperthyroidism (serum fT4, 16.2 pmol/L; serum fT3, 21.5 pmol/L; TSH, 0.05 mIU/L) from the study.
A second limitation is that our small sample has an overrepresentation of higher-educated women, probably because we excluded mothers exposed to tobacco smoke (both active and passive).
