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The strong fluorescence of fimbrial mucosa may limit the applicability of this technique in young women, however, because phototoxic damage cannot be excluded at present.
This possibility cannot be excluded at present, and will only be resolved when further structural information on the PfEMP1 NTS-didomain is available.
In colon cancer cells, Dkk4 was shown to promote cell migration in a Wnt-independent cascade [37], so that an action on hair follicle development through a Wnt-independent pathway cannot be completely excluded at present.
The possibility that Wg-stabilized Mad may bind to Armadillo/β-catenin, Pangolin/lef1, Legless/bcl9 and Pygopus independently of nearby Mad binding sites cannot be excluded at present.
Our model, which relies on the assignment of the Cα scaffold into a low resolution map, is in agreement with a variety of experimental data derived from mutagenesis analyses, as discussed below, although small deviations from the real structure cannot be excluded at present.
Under these circumstances, and because the majority of locally available material belong to only two basic genotype spectra, it cannot be excluded at present that microclimatic variations, in particular precipitation, may be a factor that partially determines the spatial distribution of these genotypes, alongside management practices.
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Although our study clearly indicates that AICD or ALID2 are on their own not essential transcriptional regulators of tested target genes in adult prefrontal cortex, we cannot exclude at present that other APP family members (including APLP1) may at least partially compensate for a single gene deficiency.
The effect of the α6B variant on cell proliferation in vitro appeared sufficient to prevent expansion of these cultures although the potential low grade contribution of apoptosis or autophagy cannot be excluded at the present time.
However, several questions remain regarding a causative role of soy consumption in reducing breast cancer risk; the possibility that the association simply reflects other factors/'healthy' lifestyle affecting breast cancer risk cannot be excluded at the present time.
However, we cannot exclude at the present time a role for adaptive immune responses in the progression of emphysematous lesions induced by cigarette smoking.
A large study of individuals with normal glucose tolerance at baseline showed a very low 8-year incidence of type 2 diabetes if fatty liver had been excluded at baseline, whereas if present, the hazard ratio for diabetes was 5.5 (range 3.6 8.5) (74).
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