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Data from these patients were included by extrapolation when using the two original populations, but not for the post hoc analysis with a more recent Danish population (in which patients with a birthweight <3 kg were excluded as per the comparison population; n = 304).
19 papers were excluded as per our criteria, leaving 531 included studies.
Of these 95 were excluded as per pre-specified exclusion criteria (Fig. 1) and inability to sample patients for 2 months (September and October) due to logistic reasons.
The arm including Fluoxetine treatment was excluded as per inclusion criteria.
Lactose intolerance was excluded as per subject profession or previous diagnosis.
A total of 312 women were excluded as per the exclusion criteria afore-described.
Similar(46)
After sequentially excluding, as per the exclusion criteria, 120 281 patients with prior diagnosis of cardiovascular disease, 2253 with invalid dates, 439 740 aged <35 years or ≥75 years, 114 123 with missing Townsend scores, 28 148 patients with a pre-existing diabetes diagnosis, and 9824 patients with prior statin use, the analysed cohort consisted of 1 072 800 patients (see table 1).
Sixty-two eligible patients were recruited (31 in each arm), although 18 were lost to follow-up and subsequently excluded, as only a per-protocol analysis was performed.
Neurological and respiratory domains were also excluded, as their involvement per se indicates severe disease unlikely to respond to enzyme replacement therapy and achieve minimal disease status.
28 29303132 32 Four studies were excluded as risks were presented per category of pollutant concentration rather than per unit increment, the increment was not defined, or the effect estimates were not presented as either relative risks or odds ratios.
In Author response image 2A we show two-color analysis of false-positive 58α-β cells binding E641, OVA, or both (39 of 500,000) after incubation with E641-APC, OVA-PerCP-Cy5.5, and MCC-PE tetramers as in Figure 4. Author response image 2B then shows that the false positive cells binding both have largely been eliminated after those bound to MCC have been excluded as a dump (2 per 500,000).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com